Alex Bortvin
Staff Member
MD, MS (Biochemistry)
Pirogov’s Moscow Medical Institute
Ph.D. (Genetics)
Harvard University
Office Telephone:
Lab Telephone:
Department Fax:
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(410) 246-3034
(410) 246-3044
(410) 243-6311
Alex Bortvin |
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BORTVIN LAB
RESEARCH INTERESTS
- Small RNAs in germ cell development
- Origin of germ cells
- Epigenetic programming of development
REPRESENTATIVE PUBLICATIONS
Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R.
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.
Development. 2003 Apr;130(8):1673-80.
Bortvin A, Goodheart M, Liao M, Page DC.
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.
BMC Dev Biol. 2004 Feb 23;4(1):2.
Sarah F.C. Soper, Godfried W. van der Heijden, Tara C. Hardiman, Mary Goodheart, Sandra L. Martin, Peter de Boer, and Alex Bortvin.
Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis.
2008 Developmental Cell, 15(2), 285-297.
van der Heijden, G.W. and Alex Bortvin
Transient relaxation of transposon silencing at the onset of mammalian meiosis.
Epigenetics 2009 4(2).
LAB MEMBERS
Julio Castaneda, Predoc Fellow Pavol Genzor, Predoc Fellow Shreyas Jadhav, Post-Doc Fellow Safia Malki, P/D Fellow Godfried Van der Heijden, P/D Fellow Neil Vranis, Student Assistant
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