Alex Bortvin

Staff Member

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MD, MS (Biochemistry)
Pirogov’s Moscow Medical Institute

Ph.D. (Genetics)
Harvard University

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RESEARCH INTERESTS

REPRESENTATIVE PUBLICATIONS

Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R.
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.
Development. 2003 Apr;130(8):1673-80.

Bortvin A, Goodheart M, Liao M, Page DC.
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.
BMC Dev Biol. 2004 Feb 23;4(1):2.

Sarah F.C. Soper, Godfried W. van der Heijden, Tara C. Hardiman, Mary Goodheart, Sandra L. Martin, Peter de Boer, and Alex Bortvin.
Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis.
2008 Developmental Cell, 15(2), 285-297.

van der Heijden, G.W. and Alex Bortvin.
Transient relaxation of transposon silencing at the onset of mammalian meiosis.
Epigenetics 2009 4(2).

Aravin AA, van der Heijden GW, Castañeda J, Vagin VV, Hannon GJ, Bortvin, A.
Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice.
PLoS Genet 5(12): e1000764. doi:10.1371/journal.pgen.1000764 (2009)

van der Heijden G. W. and Alex Bortvin.
Defending the Genome in Tudor Style.
Developmental Cell (2009), doi:10.1016/ j.devcel.2009.11.007

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