Alex Bortvin

Staff Member


MD, MS (Biochemistry)
Pirogov’s Moscow Medical Institute

Ph.D. (Genetics)
Harvard University

Office Telephone:
Lab Telephone:
Department Fax:
Email:
(410) 246-3034
(410) 246-3044
(410) 243-6311
Alex Bortvin

Untitled Page

BORTVIN LAB


RESEARCH INTERESTS

  • Small RNAs in germ cell development
  • Origin of germ cells
  • Epigenetic programming of development

REPRESENTATIVE PUBLICATIONS

Bortvin A, Eggan K, Skaletsky H, Akutsu H, Berry DL, Yanagimachi R, Page DC, Jaenisch R.
Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.
Development. 2003 Apr;130(8):1673-80.

Bortvin A, Goodheart M, Liao M, Page DC.
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.
BMC Dev Biol. 2004 Feb 23;4(1):2.

Sarah F.C. Soper, Godfried W. van der Heijden, Tara C. Hardiman, Mary Goodheart, Sandra L. Martin, Peter de Boer, and Alex Bortvin.
Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis.
2008 Developmental Cell, 15(2), 285-297.

van der Heijden, G.W. and Alex Bortvin
Transient relaxation of transposon silencing at the onset of mammalian meiosis.
Epigenetics 2009 4(2).


LAB MEMBERS

Julio Castaneda, Predoc Fellow
Pavol Genzor, Predoc Fellow
Shreyas Jadhav, Post-Doc Fellow
Safia Malki, P/D Fellow
Godfried Van der Heijden, P/D Fellow
Neil Vranis, Student Assistant