| |
Fan,
C.-M. and Maniatis, T. (1989). Two different virus-inducible elements
are required for beta-interferon gene regulation. EMBO J. 8, 101-110.
Lenardo, M.J., Fan, C.-M., Maniatis, T. and Baltimore, D. (1989). The
involvement of NF-kappa-B in beta-interferon gene regulation reveals its
role as widely inducible mediator of signal transduction. Cell 57, 287-294.
Fan,
C.-M. and Maniatis, T. (1990). A DNA binding protein containing two widely
separated zinc finger motifs that recognize the same DNA sequence. Genes
& Development 4, 29-42.
Fan,
C.-M. and Maniatis, T. (1991). The p50 subunit of NF-kappa-B is generated
by processing of p105 through an ATP-dependent pathway. Nature 354, 395-398.
Maniatis, T., Whittemore, L.-A., Du, W., Fan, C.-M., Keller,
A., Palombella, V.J. Thanos, D.N. (1992). Positive and Negative Control
of Human Interferon-_ Gene Expression. Harvey Lecture 44, 1193-1220. Cold
Spring Harbor Press.
Fan,
C.-M. and Tessier-Lavigne, M. (1994). Patterning of Mammalian Somites
by the Surface Ectoderm and the Notochord: Evidence for Sclerotome Induction
by a Hedgehog Homolog. Cell 79, 1175-1186.
Fan,
C.-M., Porter, J., Chiang, C., Chang, D.T., Beachy, P.A., and Tessier-Lavigne,
M. (1995). Long-Range Sclerotome Induction by Sonic Hedgehog: Direct Role
of the Amino-Terminal Cleavage Product and Modulation by the cyclic-AMP
Signaling Pathway. Cell 81, 457-465.
Muenke, M., Bone, L., Mitchell, H., Hart, I., Walton, K.,
Hall-Johnson, K., Ippel. E., Dietz-Band, J., Karloy, K., Fan, C.-M., Tessier-Lavigne,
M., and Patterson, D. (1995). Physical Mapping of the Holoprosencephaly
Critical Region in 21q22.3, Exclusion of SIM2 as a Candidate Gene for
HPE, and Mapping of SIM2 to a Region of Chromosome 21 Important for Down
Syndrome. The American Journal of Human Genetics 57, 1074-1079
Pourquie,
O., Fan, C.-M., Coltey, M., Hirsinger, E., Watanabe, Y., Breant, C., Francis-West,
P., Brickell, P., Tessier-Lavigne, M., and Le Douarin, N.M. (1996). Lateral
and Axial Signals involved in Avian Somite Patterning : Role of the BMP4
Protein. Cell 84, 461-471.
Fan,
C.-M., Kuwana, E., Bulfone, A., Fletcher, C. F., Copeland, N. G., Jenkins,
N. A., Crews, S., Salvador, M., Puelles, L., Rubenstein, J. L. R., and
Tessier-Lavigne, M. (1996). Expression Patterns of Two Murine Homologs
of Drosophila single-minded Suggest Possible Roles in Embryonic Patterning
and in the Pathogenesis of Down Syndrome. Molecular and Cellular Neuroscience
7, 1-16.
Mastick, G.S., Fan, C.-M., Tessier-Lavigne, M., Serbedzija, G.N., MaMahon,
A.P., Easter, S.S., Jr. (1996). Early Deletion of Neuromeres in Wnt-1-/-
Mutant Mice: Evaluation by Morphological and Molecular Markers. The Journal
of Comparative Neurology 374, 246-258.
Probst,
M.R., Fan, C.-M.,Tessier-Lavigne, M., and Hankinson, O. (1997). Two Murine
Homologs of the Drosophila single-minded Protein that Interact with the
Mouse Aryl Hydrocarbon Receptor Nuclear Translocator Protein. Journal
of Biological Chemistry 272, 4451-4457.
Michaud,
J. and Fan, C.-M. (1997). Single-minded - Two Genes, Three Chromosomes.
Genome Research 7, 569-571.
Fan,
C.-M., Lee, C.S., and Tessier-Lavigne, M. (1997) A Role for WNT Proteins
in Induction of Dermomyotome. Developmental Biology 191, 160-165.
McMahon,
J., Takada, S., Zimmerman, L.B., Fan, C.-M., Harland, R.M., and McMahon,
A.P. (1998) Noggin-mediated antagonism of BMP signaling is required for
growth and patterning of the neural tube and somite. Genes & Development
12, 1438-1452.
Michaud,
J., Rosenquist, T., May, N.R., and C.-M. Fan. (1998). Development of neuroendocrine
lineages requires the BHLH-PAS transcription factor SIM1. Genes &
Development 12, 3264-3275.
Lee,
C.S., Buttitta, L., May, N.R., Kispert, A., and C.-M. Fan. (2000). SHH-N
upregulates Sfrp2 in the somitic mesoderm to mediate its competitive action
with WNT1 and WNT4. Development 127, 109-118.
Michaud, J.L., De Rossi, C., May, N.R., Holdener, B., and C.-M. Fan. (2000).
ARNT2 acts as the dimerization partner of SIM1 for the development of
the hypothalamus. Mechanism of Development 90, 253-261.
Epstein,
D.J., Martinu, L., Michaud, J.L., Losos, K.M., Fan, C.-M., and A.-L. Joyner.
(2000). Members of the bHLH-PAS family regulate Shh transcription in forebrain
regions of the mouse CNS.
Development 127, 4701-4709.
Lee,
S.C. and C.-M. Fan. (2001). Embryonic expression patterns of the mouse
and chick Gas1 genes. Mechanism of Development 101, 293-297.
Lee,
C.S., May, N.R., and C.-M. Fan. (2001). Transdifferentiation of the ventral
retinal pigmented epithelium to neural retina in the Graowth Arrest Specific
Gene 1 mutant. Developmental Biology 236, 17-29.
Liu,
Y., May, N.R., C.-M. Fan. (2001). Growth Arrest Specific Gene 1 is a positive
growth regulator for the cerebellum. Developmental Biology 236, 30-45.
Lee,
C.S., Buttitta, L., and C.-M. Fan. (2001). Evidence that the WNT-inducible
growth arrest specific gene 1 encodes an antagonist of sonic hedgehog
signaling in the somite. Proc. Natl. Acad. Sci. USA 98, 11347-11352.
Michaud,
J.L., Boucher, F., Melnyk, A., Gauthier, F, Goshu, E., Levy, E., Mitchell,
G.A., Himms-Hagen, J., and C.-M. Fan. (2001). Human Molecular Genetics
10, 1465-1473.
Goshu,
E. Jin, H., Fasnacht, R., Spenski, M., Michaud, J.L., and C.-M. Fan. (2002).
Sim2 mutants have developmental defects not overlapping with those of
Sim1 mutants. Mol.Cell. Biol. 22, 4147-4157.
Liu,
Y., Liu, C., Yamada, Y., and C.-M. Fan. (2002). Growth arrest specific
gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory
loop in the limb. Development 129, 5289-5300.
Buttitta,
L., Tanaka, T., Chen, A., Ko, M., and C.-M. Fan. (2003) Microarray analysis
reveals novel WNT targets in the somites. Developmental Biology 258, 91-104.
Liu C, Goshu E, Wells A, Fan CM. (2003) Identification of the downstream targets of SIM1 and ARNT2, a pair of transcription factors essential for neuroendocrine cell differentiation. J Biol Chem. 278:44857-67.
Buttitta L, Mo R, Hui CC, Fan CM. (2003) Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development 130:6233-43.
Goshu E, Jin H, Lovejoy J, Marion JF, Michaud JL, Fan CM. (2004) Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus. Mol Endocrinol. 18:1251-62.
Chen AE, Ginty DD, Fan CM. (2005) Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins. Nature 433: 208-9.
Chen AE, Fan CM. (2005) Targeting gene expression in the mouse somite: adenovirus-mediated gene delivery and whole embryo culture. Genesis 42:71-6.
|
|
|