Koshland Web Site
Publications

1. Koshland, D., Meyers, S.E., and Chesick, J.P. (1977). The crystal structures of 1,3,5-trimethybenzenetricarbonyl-molybdenum and hexamethylben zenetricarbonyl-molybdenum. Acta. Cryst. B33:2013-2023.
2. Koshland, D. and Botstein, D. (1980). Secretion of &Mac178;-lactamase requires the carboxy end of the protein. Cell 20:749-760.
3. Shortle, D., Koshland, D., Weinstock, G.M., and Botstein, (1980). Segment-directed mutagenesis: Construction in vitro of point mutations limited to a small predetermined region of a circular DNA molecule. Proc. Natl. Acad. Sci. USA 77:5375-5379.
4. Koshland, D. and Botstein, D. (1982). Evidence for posttranslational translocation of &Mac178;-lactamase across the bacterial inner membrane. Cell 30:893-902.
5. Koshland, D., Sauer, R.T. and Botstein, D. (1982). Diverse effects of mutations in the signal sequence on the secretion of &Mac178;-lactamase in Salmonella typhimurium. Cell 30:903-914.
6. Koshland, D., Kent, J.C., and Hartwell, L.H. (1984). Genetic analysis of the mitotic transmission of minichromosomes. Cell 40:393-403.
7. Koshland, D. and Hartwell, L.H. (1987). The structure of sister minichromosome DNA prior to anaphase in Saccharomyces cerevisiae. Science 238:1713-1716.
8. Koshland, D., Rutledge, L., Fitzgerald-Hayes, M. and Hartwell, L.H. (1987). A genetic analysis of dicentric minichromosomes in Saccharomyces cerevisiae. Cell 48:801-812.
9. Koshland, D. and Hieter, P., Visual assay for chromosome ploidy. Recombinant DNA In, Methods in Enzymology, R.Wu and L. Grossman, eds., Academic Press, Orlando, Florida. Vol. 155:351-372.
10. Koshland, D., Mitchison, T.J., and Kirschner, M. (1988). Polewards chromosome movement driven by microtubule depolymerization in vitro. Nature 331:499-504.
11. Palmer, R.E., Koval, M., and Koshland, D. (1989). The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae. J. Cell. Biol. 109:3355-3366.
12. Palmer, R., Hogan, E., and Koshland, D. (1990). Mitotic transmission of artificial chromosomes in cdc mutants of the yeast Saccharomyces cerevisiae. Genetics 125:763-774.
13. Shero, J.H., Koval, M., Spencer, F., Palmer, R., Hieter, P., and Koshland, D. (1991). Analysis of chromosome segregation in Saccharomyces cerevisiae. Methods in Enzymol. 194:749-773.
14. Kingsbury, J. and Koshland, D. (1991). Centromere-dependent binding of yeast minichromosomes to microtubules in vitro. Cell 66:483-495.
15. Sethi, N., Monteagudo, M.C., Koshland, D., Hogan, E. and Burke, D.J. (1991). The CDC20 gene product of Saccharomyces cerevisiae, a &Mac178;-transducin homolog, is required for a subset of microtubule-dependent cellular processes. Mol. Cell. Biol. 11:5592-5602.
16. Hogan, E. and Koshland, D. (1992). Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 89:3098-3102.
17. Palmer, R.E., Sullivan, D.S., Huffaker, T. and Koshland, D. (1992). Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae. J. Cell Biol. 119:583-593.
18. Koshland, D. (1992). Unifying forces for chromosomes in mitosis. Curr. Biol. 2:569-571.
19. Kingsbury, J. and Koshland, D. (1993). Centromere function on minichromosomes isolated from budding yeast. Mol. Biol. Cell, 4:859-870.
20. Guacci, V., Yamamoto, A., Strunnikov, A., Kingsbury, J., Hogan, E., Meluh, P. and Koshland, D. (1993). Structure and function of chromosomes in mitosis of budding yeast. Cold Spring Harbor Symp. Quant. Biol. 58:677-685.
21. Strunnikov, A., Larionov, V.L. and Koshland, D. (1993). SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein family. J. Cell Biol. 123:1635-1648.
22. Guacci, V., Hogan, E. and Koshland, D. (1994). Chromosome condensation and sister chromatid pairing in budding yeast. J. Cell Biol. 125:517-530.
23. Koshland, D. (1994). Mitosis: back to the basics. Cell 77:951-954.
24. Strunnikov, A.V., Kingsbury, J. and Koshland, D. (1995). CEP3 encodes a centromere protein of Saccharomyces cerevisiae. J. Cell Biol. 128:749-760.
25. Saunders, W.S., Koshland, D., Eshel, D., Gibbons, I.R. and Hoyt, M.A. (1995). Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation. J. Cell. Biol. 128:617-624.
26. Strunnikov, A.V., Hogan, E. and Koshland, D. (1995).SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family. Genes Dev. 9:587-599.
27. Yamamoto, A., DeWald, D.B., Boronenkov, I.V., Anderson, R.A., Emr. S.D. and Koshland, D. (1995). Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol. Biol. Cell 6:525-539.
28. Meluh, P. and Koshland, D. (1995). Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein, CENP-C. Mol. Biol. Cell 6:793-807.
29. Yamamoto, A., V. Guacci and Koshland,D. (1996). Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J. Cell Biol. 133:85-97.
30. Yamamoto, A., V. Guacci and Koshland, D. (1996). Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J. Cell Biol. 133:99-110.
31. Basrai, M.A., Kingsbury, J., Koshland, D., Spencer, F. and Hieter, P. (1996). Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2838-2847.
32. Koshland, D. and Strunnikov, A (1996). Mitotic chromosome condensation. Ann. Rev. Cell Biol. 12:305-333.
33. Cohen-Fix, C., Peters, J.-M., Kirschner, M.W. and Koshland, D. (1996). Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC dependent degradation of the anaphase inhibitor, Pds1p. Genes Dev. 10:3081-3093.
34. Guacci, V., Hogan, E., and Koshland, D. (1997). Centromere position in budding yeast: evidence for anaphase A. Mol. Biol. Cell 8:957-972.
35. Guacci, V., Koshland, D. and Strunnikov, A. (1997). A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91:47-57.
36. Cohen-Fix, O. and Koshland, D. (1997). The metaphase to anaphase transition: avoiding a mid-life crisis. Curr. Opin. Cell Biol. 9:800-806.
37. Meluh, P. and Koshland, D. (1997). Insights into budding yeast centromere composition and assembly revealed by in vivo crosslinking. Genes Dev. 11:3401-3412.
38. Cohen-Fix, O. and Koshland, D. (1997). The anaphase inhibitor of S. cerevisiae, Pds1p, is a mitosis specific target of the DNA damage checkpoint pathway. Proc. Natl Acad. Sci. USA, 94:14361-14366.
39. Meluh, P.B., Yang, P., Glowczewski, L., Koshland, D. and Smith, M.M. (1998). Cse4p is a component of the core centromere of Saccharomyces cerevisiae. Cell 98:607-613.
40. Hyland, K. M., Kingsbury, J., Koshland, D., and Hieter, P. (1999). Ctf19p: A novel kinetochore protein in Saccharomyces cerevisiae and a potential link between the kinetochore and mitotic spindle. J. Cell Biol. 145:15-28.
41. Skibbens, R. V., Corson, L. B., Koshland, D., and Hieter, P. (1999). Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. Genes Dev. 13:307-319.
42. Cohen-Fix, O. and Koshland, D.E. (1999). Pds1p of budding yeast has dual roles: inhibition of anaphase initiation and regulation of mitotic exit. Genes Dev. 13:1950-1959.
43. Megee, P.C. and Koshland, D. (1999). Functional assay for centromere-associated sister chromatid cohesion. Science 285:254-257.
44. Megee, P.C. , Mistrot, C., Guacci, V. and Koshland, D. (1999). The centromeric sister chromatid cohesion site directs Mcd1p binding to adjacent sequences. Molecular Cell 4:445-450.
45. Lavoie, B.D., Tuffo, K.M., Oh, S., Koshland D. and Holm, C. (2000). Mitotic chromosome condensation requires Brn1p, the yeast homologue of barren. Mol. Biol. Cell 11:1293-1304.
46. Koshland, D.E. and Guacci, V. (2000). Sister chromatid cohesion: the beginning of a long and beautiful relationship. Curr. Opin. Cell Biol. 12:297-301.
47. Laloraya, S., Guacci, V. and Koshland, D. (2000). Chromosomal addresses of the cohesin-component, Mcd1p. J. Cell Biol. 151:1047-1056.
48. Hartman, T., Stead, K., Koshland, D. and Guacci, V. (2000). Pds5p is an essential chromosomal protein required for both sister chromatid cohesion and condensation in Saccharomyces cerevisiae. J. Cell Biol. 151:613-626.
49. Lavoie, B., Hogan, E. and Koshland D.E. (2002). In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J. Cell Biol. 156:805-815.
50. Huang, D. and Koshland, D. (2003). Chromosome integrity in Saccharomyces cerevisiae: the interplay of DNA replication initiation factors, elongation factors, and origins. Genes Dev. 17:1741-1754.
51. Milutinovich, M. and Koshland, D.E. (2003). Molecular biology. SMC complexes-wrapped up in controversy. Science 300:1101-1102.
52. Yu, H.G. and Koshland, D. (2003). Meiotic condensing is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages. J. Cell Biol. 163:937-947.
53. Lavoie, B.D., Hogan, E. and Koshland, D. (2004). In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding. Genes Dev. 18:76-87.
54. Weber, S.A., Gerton, J., Polancic, J.E., DeRisi, J.L, Koshland, D., Megee, P.C. (2004). The kinetochore is an enhancer of pericentric cohesin binding. PloS Biol. 2:E260.
55. Glynn, E.F., Megee, P.C., Yu, H.G., Mistrot, C., Unal, E., Koshland, D.E., DeRisi, J.L. and Gerton, J.L. (2004). Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae. PLoS Biol. 2:E259.
56. Unal, E., Arbel-Eden, A., Sattler, U., Shroff, R., Lichten, M., Haber, J.E. and Koshland, D. (2004). DNA damage response pathway uses histone modification to assemble a double-strand break specific cohesin domain. Molecular Cell 16:991-1002.
57. Huang, C.E., Milutinovich, M. and Koshland D. (2005). Rings, bracelet or snaps: fashionable alternatives for Smc complexes. Phil. Trans.: Biological Sciences 360:537-542.
58. Yu, H.G., and Koshland D. (2005). Chromosome morphogenesis: condensin-dependent cohesin removal during meiosis. Cell 123:397-407.
59. Milutinovich, M., Ünal, E., Ward, C., Skibbens, R.V. and Koshland D. (2007). A multi-step pathway for the establishment of sister chromatid cohesion. PloS Genetics Jan 19;3(1):e12 [Epub ahead of print].
60. Yu, H.G. and Koshland, D. (2007). The aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis. Journal of Cell Biology Mar 19: [Epub ahead of print].

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